xt72bv79vr8k https://exploreuk.uky.edu/dips/xt72bv79vr8k/data/mets.xml University of Kentucky University of Kentucky Chemistry Department 20140425 A brochure for the Naff Symposium, an event hosted by the University of Kentucky Chemistry Department supported by the Anna S. Naff Endowment Fund. This brochure belongs to the University of Kentucky Chemistry Department Records collection, accession number 2014ua075. archival material English University of Kentucky Chemistry Department Contact the Special Collections Research Center for information regarding rights and use of this collection. University of Kentucky Chemistry Department Naff Symposium brochures 40th Annual Symposium on Chemistry and Molecular Biology: "Complexity and Self Assembly" text 40th Annual Symposium on Chemistry and Molecular Biology: "Complexity and Self Assembly" 2014 2017 true xt72bv79vr8k section xt72bv79vr8k t >5 W” ANNUAL SYMPOSIUM ON
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23 OHEMISTRV O MOLECULAR BIOLOGY
8 AM HEBlSTRATlUN 8 CUNHNENTAL BREAKFAST internal molecular scaffolds, which also orient most of the cell’s D J 00:)
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UNIVERSITY [ll KENIUCKV
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ESTABLISHED BY M. BENIUN NAEE IN MEMORY BE ANNA S. NAEE
ERIBAV, APRIL 25. EBIAI I 9 AM I AUBIIURIUM. WILLIAM I. VBUNE LIBRARY
‘7 Hao Yan is the Milton D. Glick Distinguished Professor in Chemistry and Biochemistry and
I Director of the Center for Molecular Design and Biomimicry in the Biodesign Institute
7.1) "f at Arizona State University. Hao Yan studied chemistry and earned his bachelor’s degree at
..,. ‘ Shandong University, China. He obtained his Ph.D. in chemistry under Professor N. C. Seeman
3‘5" 7' at New York University in 2001, working on design and construction of sequence dependent
. A DNA nanomechanical devices. He then moved to the Computer Science Department at Duke
% _. University, where he continued to explore his interests in DNA based molecular computing and
programming. He joined Arizona State University as assistant professor in the Department of
Chemistry and Biochemistry in 2004. In 2008, he was promoted with early tenure directly to
full professor. The focus of his research is to use nature’s design rules as inspiration to advance
biomedical, energy-related, and other technological innovations through the use of self—assembling molecules
and materials. He aims to create intelligent materials with better component controls at the molecular level. He
is leading an interdisciplinary team to design bio-inspired molecular building blocks and program their higher
order assembly into systems that will perform complex functions. Dr. Yan has published more than 130 papers
and has received honors including the Rozenberg Tulip Award in DNA Computing, Alfred P. Sloan Research
Fellowship, NSF Career Award, AFOSR Young Investigator Award.
_ . .;, Donald Ingber is the Founding Director of the Wyss Institute for Biologically Inspired
{ If" I “as Engineering at Harvard University, the Judah Folkman Professor of Vascular Biology at
s. 1; Harvard Medical School and Boston Children's Hospital, and Professor of Bioengineering
" ., 2"": at the Harvard School of Engineering and Applied Sciences. He received his B.A., M.A.,
t M.Phi|., MD. and Ph.D. from Yale University. Dr. Ingber is a founder of the emerging field
$35)!“ of biologically inspired engineering, and at the Wyss Institute, he oversees a multifaceted
" effort to identify the mechanisms that living organisms use to self-assemble from molecules
’~‘ and cells, and to apply these design principles to develop advanced materials and devices
"%W_ for healthcare and to improve sustainability. He also leads the Biomimetic Microsystems
" platform in which microfabrication techniques from the computer industry are used to build
functional circuits with living cells as components. His most recent innovation is a technology for building tiny,
complex, three-dimensional models of living human organs, or ”Organs on Chips," that mimic complicated
human functions as a way to replace traditional animal-based methods for testing of drugs and establishment
of human disease models. In addition, Dr. Ingber has made major contributions to mechanobiology, tissue
engineering, tumor angiogenesis, systems biology, and nanobiotechnology. He was the first to recognize
that tensegrity architecture is a fundamental principle that governs how living cells self-organize themselves
to respond biochemically to mechanical forces, and to demonstrate that integrin receptors mediate cellular
mechanotransduction. Dr. Ingber has authored more than 375 publications and 85 patents, and has received
numerous honors. He also serves on the Board of Directors of the National Space Biomedical Research Institute,
and is a member of both the American Institute for Medical and Biological Engineering, and the Institute of
Medicine of the National Academies.
All w:1: F“ ‘ Todd Yeates is a Professor of Chemistry and Biochemistry at the University of California,
‘ ’ .3: Los Angeles. He earned his bachelor’s degree at UCLA in 1983. He stayed on at UCLA and
1.5; _ gﬁgf earned his Ph.D. in 1988. There he helped determine the crystal structure of the bacterial
“tnf'éw‘ﬁ _ _‘ photosynthetic reaction center as part of a team racing to determine the first crystal structures
, ”I of membrane proteins. He then moved to The Scripps Research Institute to do his postdoctoral
Allllllllt nil research on the structure of poliovirus with Prof. James Hogle. Yeates returned to UCLA in
I‘l)l , ll," Lug 1990 to join the faculty in the Department of Chemistry and Biochemistry. His interdisciplinary
' I research, combining molecular biology with computing and mathematics, has focused on
. tr 7 " ‘93 macromolecular structure and computational genomics. His varied research findings include:
an explanation for why proteins crystallize in certain favored arrangements; the development
of new equations for detecting disorder in x—ray diffraction data from protein crystals; the discovery of
thermophilic microbes rich in intracellular disulfide bonds; development of comparative genomics methods;
development of designed protein cages or ’nanohedra’; the discovery of novel topological features such as
links and slipknots that stabilize thermostable proteins; and elucidation of the structure of the carboxysome
shell and the shells of other bacterial microcompartments, which serves as primitive metabolic organelles
inside many bacterial cells. Yeates is a member of the Molecular Biology Institute, the California Nanosystems
Institute, the UCLA—DOE Institute of Genomics and Proteomics, and a Fellow of the American Association for the
Advancement of Science. He has published approximately 150 research papers.
For additional information, contact Professor Jason DeRouchey at derouchey@uky,edu.
2014 Committee: Professor Jason DeRouchey, Chair
Professor Marcelo Guzman
Professor Chris Richards
Professor Anne»Francis Miller
Professor Stephen Testa
Symposium supported by the Anna S. Naff Endowment Fund